A key aspect of type i collagen is its post. Loss of specific lamins does not affect protein levels of other lamins we analyzed the function of specific lamins in nuclear shape stability and stiffness in wild type mefs and in mefs lacking lamin a designated lamin c only or lmna lco lco cells in mefs deficient in both lamins a and c lmna and in mefs expressing a severely truncated mutant form of lamin b1 lmnb1. Lamin a is also farnesylated but it is unique among farnesylated human proteins 90.
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